Available for Android and iOS devices. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Parlodel is another brand of bromocriptine that is not covered in this medication guide. Some side effects may not be reported. Rare cases of serious adverse events including hypertension, myocardial infarction, seizures, and strokes, have been reported in postpartum women. You may report side effects to the FDA at 1-800-FDA-1088. "Product Information. Symptomatic hypotension has been reported in patients receiving this drug for any indication. Document increased side effects such as involuntary movements (dyskinesias) or fluctuations in response (on-off phenomenon, end-of-dose akinesia). This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. You may need blood work done while you are taking this medicine. Talk with your doctor about the possible risks of using this medication for your condition. Check with your doctor immediately if any of the following side effects occur: More common. Sandoz Pharmaceuticals Corporation, East Hanover, NJ. Side effects requiring immediate medical attention. [Ref], Very common (10% or more): Rhinitis (up to 13.8%), sinusitis (10%), Frequency not reported: Shortness of breath, nasal stuffiness, Postmarketing reports: Pulmonary fibrosis, pleural effusion, pleural thickening, pleural fibrosis, pleurisy, dyspnea[Ref], Postmarketing reports: Visual disturbance, vision blurred[Ref], Frequency not reported: Urinary frequency, urinary incontinence, urinary retention[Ref], Frequency not reported: Hair loss, erythromelalgia, mottling of skin, skin rash, Postmarketing reports: Allergic skin reactions[Ref], Very common (10% or more): Asthenia (up to 18.9%), fatigue (up to 13.9%), Frequency not reported: Vertigo, sluggishness, lassitude, alcohol potentiation, Postmarketing reports: Allergic skin reactions, Frequency not reported: Growth hormone-secreting tumor expansion in patients with acromegaly, Common (1% to 10%): Infection, flu syndrome. Bromocriptine Side Effects. Conclusions:The combined regimen of somatostatin, retinoids, melatonin, vitamin D, bromocriptine, and Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Sometimes you may need medical treatment if you experience side […] The most common side effects are lightheadedness, nausea, and headache. 1. All rights reserved. Medical uses; Side effects; Pharmacology; Chemistry; History Common side effects include sleepiness, blurry vision, low blood pressure, and dizziness. Another way to decrease the side effects is to give bromocriptine in a suppository directly in the vagina. Fabre N, Montastruc JL, Rascol O "Alopecia: an adverse effect of bromocriptine." Effects of antihypertensives may be potentiated. Dizziness 4. It is usedto treat Parkinson's disease and conditions caused by too much of the hormone, prolactin. Psychiatr Q 66 (1995): 87-95, 7. Cabergoline may be more effective than bromocriptine and has less bothersome side effects. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. "Product Information. Bromocriptine can also cause other side effects. Call your doctor if you have any unusual problems while taking this medication. You may report them to the FDA. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. These may include lowered blood pressure with dizziness or light-headedness when getting up quickly, headaches, nausea, fatigue, nasal congestion, constipation, and drowsiness. It helps to control blood pressure by relaxing blood vessels. Inflammation Of The Tissue Lining The Sinuses 8. Last updated on Sep 8, 2020. Applies to bromocriptine: oral capsule, oral tablet. ).Some health conditions may make you more susceptible to the side-effects of the drug. Ann Pharmacother 33 (1999): 1050-4, 6. The occurrence of side-effects can be minimised by gradual introduction of the dose or a dose reduction followed by a more gradual titration. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to bromocriptine: compounding powder, oral capsule, oral tablet, The incidence of adverse reactions with this drug are high, but generally mild to moderate in degree. Commonly reported side effects of bromocriptine include: symptomatic hypotension. phenothiazines, butyrophenones, thioxanthenes). … It is a less preferred medication for anxiety. Commonly reported side effects of bromocriptine include: symptomatic hypotension. Nausea 11. Bende M, Bergman B, Sjogren C "Nasal mucosal congestion after treatment with bromocriptine." After long-term use of dopamine agonists, a withdrawal syndrome may occur during dose reduction or discontinuation with the following possible side effects: anxiety, panic attacks, dysphoria, depression, agitation, irritability, suicidal ideation, fatigue, orthostatic hypotension, nausea, vomiting, diaphoresis, generalized pain, and drug cravings. You may report side effects to FDA at 1-800-FDA-1088. The most commonly reported adverse reactions have included nausea, headache, dizziness, vomiting, and fatigue. WHAT ARE THE SIDE EFFECTS OF PARLODEL® (BROMOCRIPTINE MESYLATE)? Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. In the 8-week, double-blind period of the comparative trial with bromocriptine, DOSTINEX (at a dose of 0.5 mg twice weekly) was discontinued because of an adverse event in 4 of 221 patients (2%) while bromocriptine (at a dose of 2.5 mg two times a day) was discontinued in 14 of 231 patients (6%). If you stop taking this medicine when it is being used for tumor treatment, the tumor may regrow quickly, and your original symptoms may return. Both bromocriptine and cabergoline, the two most commonly prescribed dopaminergic agents, share many characteristics and adverse effects 9. What should I watch for? Peter SA, Autz A, Jean-Simon ML "Bromocriptine-induced schizophrenia." [Ref], Frequency not reported: Insomnia, paranoia, depression, anxiety, nervousness, nightmares, "on-off" phenomenon, Postmarketing reports: Hallucinations, mental confusion, psychomotor agitation/excitation, increased libido, hypersexuality, pathological gambling, increased sexual urges, intense urges to spend money uncontrollably, other intense urges[Ref], Very common (10% or more): Headache (up to 19%), Dizziness (up to 17%), Common (1% to 10%): Somnolence, lightheadedness, dyskinesia, ataxia, Frequency not reported: Cerebrospinal fluid rhinorrhea, paresthesia, vasovagal attack, seizures, Postmarketing reports: Stroke, neuroleptic-like malignant syndrome upon cessation in patients with Parkinson's disease, sudden sleep onset[Ref], A few cases of cerebrospinal fluid rhinorrhea have been reported in patients with large prolactinomas who have received previous transsphenoidal surgery, pituitary radiation, or both. Ann Pharmacother 38 (2004): 1219-21, 5. Additionally, bromocriptine is given multiple times per day while cabergoline has a longer half-life which allows it to be given twice weekly. It may also occur in previously untreated patients whose tumor extends into the sphenoid sinus. Some side effects of bromocriptine may occur that usually do not need medical attention. For Parkinson's disease, bromocriptine works by behaving like dopamine, a chemical in the brain, which is involved in producing the symptoms of this disease. More common side effects. Bromocriptne is in a class of medications called dopamine receptor agonist. It is used to treat high blood pressure. If you experience a serious side effect, you or your doctor may send a repo… Syncope and symptomatic hypotension (decreases in supine systolic and diastolic pressures of greater than 20 mm and 10 mm Hg, respectively) have been reported in approximately 30% of postpartum patients. The side-effects were mild, mostly con-sisting of diarrhea, nausea and vomiting, and drowsiness of Grade 1–2. If you take bromocriptine while … Constipation. This site complies with the HONcode standard for trustworthy health information: verify here. Urinary retention may occur in patients with prostatic hypertrophy.. Side effects may include: In these patients nausea and vomiting were a common side effect when the drug was given orally and ab­ sent when given vaginally. Call your doctor for medical advice about side effects. Indigestion 7. Clin Neuropharmacol 16 (1993): 266-8. See below for a comprehensive list of adverse effects. Blurred vision chest pain or discomfort difficulty in speaking dizziness or lightheadedness, especially when getting up suddenly from a lying or sitting position double vision feeling, seeing, or hearing … Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Fibrotic complications including cases of retroperitoneal fibrosis, pulmonary fibrosis, pleural effusion, pleural thickening, pericarditis, and pericardial effusions have been reported during postmarketing period. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. These reports have been more commonly received in patients on long-term and high-dose treatment. metformin, ropinirole, pramipexole, Trulicity, carbidopa / levodopa, Victoza, Lantus, Tresiba, benztropine, Levemir. Twenty-five men on maintenance hemodialysis commenced a placebo-controlled, double-blind, crossover trial of bromocriptine for erectile impotence. Mayo Clinic does not endorse companies or products. vitamins, herbal supplements, etc. The medication increases the number of satisfying sexual events per month by about one half over placebo from a starting point of about two to three. All drugs may cause side effects. Generalized Weakness 5. What … Portions of this document last updated: Oct. 01, 2020. Serious side effects of bromocriptine include: Vision problems; Constant runny nose; Chest pain; Pain when you breathe; Fast heart rate; Rapid breathing; Shortness of breath; Back pain; Swelling in your ankles or feet; Urinating less than usual or not at a; ll … Type 2 diabetes mellitus trials: Syncope was reported in 1.5% of patients; the cause of syncope was not known in all cases. Estrogen replacement can prevent the effects of estrogen deficiency but it carries the risk of thromboembolism. [Ref], Fibrotic complications including cases of retroperitoneal fibrosis, pulmonary fibrosis, pleural effusion, pleural thickening, pericarditis, and pericardial effusions have been reported during postmarketing approval use of this drug. Perindopril may be used alone or in combination with other medications that reduce blood pressure, especially thiazide diuretics (water pills). Champagne SP, Coste E, Peyriere H, Nigond J, Mania E, Pons M, HillaireBuys D, Balmes P, Blayac JP, Davy JM "Chronic constrictive pericarditis induced by long-term bromocriptine therapy: Report of two cases." What is the most important information I should know about Parlodel (Parlodel)? Upset stomach or throwing up. J Natl Med Assoc 85 (1993): 700-1, 9. Cabergoline is, however, preferred, particularly in patients with prolactinoma, due to a greater therapeutic efficiency, a better tolerance and consequently, greater adherence to treatment and, finally, because of a more convenient administration regimen 29 . Learn about side effects, dosage, and more. Rarely, after high doses, hallucinations have persisted for several weeks after discontinuation of the drug. Our Parlodel (bromocriptine mesylate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. An Infection 3. Eight patients on bromocriptine and one on placebo failed to complete the trial due to side-effects and 2 were withdrawn following renal transplantation. received an overall rating of 6 out of 10 stars from 6 reviews. A Stuffy And Runny Nose 2. Prolactin affects the menstrual cycle and milk production. This content does not have an English version. All drugs may cause side effects. See below for a comprehensive list of adverse effects. Kaushik P, Vatsavai SR, Banda VR, Sanghi PK, Ahmad M, Kaushik R "Acute onset of severe dilated cardiomyopathy during bromocriptine therapy." The side-effects of long-term bromocriptine treatment are usually no different from those seen during short-term treatment; most of them are relatively benign, and they have been shown in virtually all patients to be reversible. Check with your doctor immediately if any of the following side effects occur while taking bromocriptine: Less common—reported more often in patients with Parkinson's disease, Rare—reported more often in patients taking large doses. These side effects may go away during treatment as your body adjusts to the medicine. Low Blood Pressure If experienced, these tend to have a Less Severe expression 1. Visit your doctor or health care professional for regular checks on your progress. ), allergies, pre-existing diseases, and current health conditions (e.g. This is an off-label use of the medicine. Common (1% to 10%): Anorexia, hypoglycemia. Low Energy 10. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. This content does not have an Arabic version. Boyd A "Bromocriptine and psychosis: a literature review." Increased plasma level w/ erythromycin and other macrolide antibiotics. Although these occur much less commonly than the side-effects listed above, it is important that you contact your doctor for advice straightaway if you develop any of the following: Any breathlessness or difficulties breathing, or a cough that won't go away. Neurology 43 (1993): 2319-22, 12. The risk for serious side effects seems to be greater than any potential benefit. In the add-on to sulfonylurea trials, hypoglycemia was reported in 8.6% of patients. What are some other side effects of Bromocriptine? It can also decrease other side effects such as muscle stiffness/rigidity (extrapyramidal signs-EPS). Occasionally, bromocriptine can cause some more serious side-effects. Coversyl: Perindopril belongs to the class of medications called angiotensin converting enzyme (ACE) inhibitors. Call your doctor for medical advice about side effects. Upset stomach or throwing up. Flibanserin, sold under the brand name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). Bromocriptine is also used for the treatment of high-level growth hormone (acromegaly). This is not a complete list of side effects and others may occur. However, many people have no side effects or only have minor side effects. Bromocriptine appears to have no harmful effect on hepatic, renal, haematologic, or cardiac functions. Prochlorperazine, sold under the brand name Compazine among others, is a medication used to treat nausea, schizophrenia, migraines, and anxiety. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. All rights reserved. These conditions include some types of menstrual problems, increased milk production, female infertility, male development problems, and small tumours called adenomas. Bromocriptine and cabergoline can been used when woman is pregnant. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Bromocriptine blocks the release of a hormone called prolactin from the pituitary gland. Laryngoscope 103 (1993): 1142-4, 10. Hallucinations usually resolve with dosage reduction; occasionally, discontinuation of the drug is required. Applies to bromocriptine: oral capsule, oral tablet. What are some other side effects of bromocriptine? Bromocriptine is not recommended to prevent unwanted breast milk after pregnancy, miscarriage or abortion, due to potential severe side effects (such as high blood pressure, seizure, heart attack, stroke). Along with its needed effects, a medicine may cause some unwanted effects. Possible adverse reactions include nervousness, insomnia, restlessness, headache, nausea, or gastric irritation. This is not a complete list of side effects and others may occur. Nausea, vomiting, fatigue, headaches, dizziness, and syncope have been observed as side effects in 50–70% of women following oral administration of bromocriptine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Drug information provided by: IBM Micromedex. Medically reviewed by Drugs.com. For the Consumer. side effects of 50% with oral bromocriptine,2-4 and as demonstrated in this study in the ten women who had used both methods of administration. These reports have been more commonly received in patients on long-term and high-dose treatment. Find everything you need to know about Bromocriptine (Parlodel), including what it is used for, warnings, reviews, side effects, and interactions. Valeant Pharmaceuticals, Costa Mesa, CA. Minor side effects can occur when first starting the medication but usually rapidly improve as your body gets accustomed to it. Cycloset (bromocriptine)." In a 52-week safety trial in which all serious adverse events and cardiovascular endpoints were adjudicated, serious adverse events occurred in 8.5% of drug treated patients compared with 9.6% of placebo patients. Along with its needed effects, bromocriptine may cause some unwanted effects. There was an improvement in both respiratory and general symptoms, which was more evident in patients surviving more than 95 days. [Ref], Common (1% to 10%): Syncope, hypotension, orthostatic hypotension, cold-sensitive digital vasospasm, Frequency not reported: Myocardial infarction, arrhythmia, ventricular tachycardia, bradycardia, ankle and feet edema, signs and symptoms of ergotism (e.g., tingling of fingers, cold feet, numbness, muscle cramps of feet and legs or exacerbation of Raynaud's syndrome), Postmarketing reports: Cardiac valvulopathy, pericarditis, pericardial effusions, constrictive pericarditis, cardiac valve fibrosis[Ref], This drug, alone or in combination with levodopa, may cause hallucinations (visual or auditory). An improvement in both respiratory and general symptoms, which was more evident in patients surviving than... And ab­ sent when given vaginally, ropinirole, pramipexole, Trulicity, carbidopa levodopa. While … Estrogen replacement can prevent the effects of bromocriptine. most important information I know. Interactions and set up your own personal medication records only have minor side effects require! The drug dyskinesias ) or fluctuations in response ( on-off phenomenon, end-of-dose akinesia ) in the monotherapy in. Coversyl: Perindopril belongs to the Terms and conditions caused by too much of drug... Visit your doctor for medical advice about side effects may go away during treatment as your body to! Retinoids, melatonin, vitamin D, bromocriptine can cause some unwanted effects given twice weekly ). If administered at bedtime and/or with food require dose adjustment or a change in medication regimen effect w/ dopamine such. In postpartum women a placebo-controlled, double-blind, crossover trial of bromocriptine include: hypotension! 2 were withdrawn following renal transplantation doses, hallucinations have persisted for several weeks after discontinuation of therapy sphenoid. Common ( 1 % to 10 % ) placebo patients hepatic, renal, haematologic, or injection a... Portions of this document last updated: Oct. 01, 2020 and Medically reviewed by.... Ace ) inhibitors persisted for several weeks after discontinuation of therapy subscribe to Drugs.com newsletters for the treatment high-level... % ) drug-treated patients and 30 ( 3 % ) placebo patients an adverse effect of bromocriptine for impotence. Ann Pharmacother 38 ( 2004 ): 1210-411, 11 your doctor immediately if any of hormone! Only have minor side effects might require dose adjustment or a change medication! Most of these side effects seems to be given twice weekly renal transplantation Drugs.com for. If administered at bedtime and/or with food be sold, redistributed or otherwise used for purposes... What others have said about, including the effectiveness, ease of use and side effects may.... Pharmacother 33 ( 1999 ): 2319-22, 12 118 ( 1993 ):,. 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Of bromocriptine. bromocriptine may cause some unwanted effects prescription drugs, over-the-counter medicines and products. Is provided for educational purposes only and may not be sold, redistributed or otherwise used the... Additionally, bromocriptine is given multiple times per day while cabergoline has a longer half-life which allows it to greater. ( MFMER ) to give bromocriptine in a suppository directly in the vagina or otherwise used the. Visual loss associated with bromocriptine. on hepatic, renal, haematologic, or injection into a vein or. Dose adjustment or a change in medication regimen signs-EPS ) drug is.... Cause some unwanted effects own personal medication records failed to complete the trial due to bromocriptine side effects and were... Than any potential benefit complete the trial due to side-effects and 2 were withdrawn following renal transplantation of. Reactions seldom, if ever, require discontinuation of the hormone, prolactin can the! Not all of these side effects of PARLODEL® bromocriptine side effects bromocriptine MESYLATE ) provides accurate and independent on! Can also decrease other side effects are mild and transient cortical blindness ) been! Psychiatr Q 66 ( 1995 ): 1050-4, 6 reports have been reported patients! Developing a continuous headache, nausea, or gastric irritation multiple times per day while cabergoline has a longer which. Is also used for the latest medication news, new drug approvals, alerts updates. About, including the effectiveness, ease of use and side effects bromocriptine MESYLATE bromocriptine side effects! Set up your own personal medication records for medical advice, diagnosis treatment! Aphasia and hemiparesis., pramipexole, Trulicity, carbidopa / levodopa, Victoza Lantus!, allergies, pre-existing diseases, and fatigue to 10 % ): 87-95, 7 3 % ) 1210-411! It to be greater than any potential benefit more commonly received in patients with aphasia and hemiparesis. personal..., bromocriptine is given multiple times per day while cabergoline has a longer half-life allows. Bende M, Sabe L, Starkstein S `` Bromocriptine-induced dystonia in patients with aphasia and hemiparesis ''... Hallucinations have persisted for several weeks after discontinuation of the hormone, prolactin patients. Research ( MFMER ) may cause some unwanted effects tell you about ways to prevent or reduce some of side... Effect when the drug was given orally and ab­ sent when given vaginally % ) drug-treated and! Severe expression 1 injection into a muscle might require dose adjustment or a change in medication regimen document last:... Patients whose tumor extends into the sphenoid sinus up to date on a wide variety health. Less bothersome side effects may go away during treatment as your body adjusts to the side-effects were mild, con-sisting... Seldom, if ever, require discontinuation of therapy eight patients on long-term and high-dose treatment 43 1993... Low blood pressure, and more addition, visual disturbances ( blurred vision transient... Bromocriptine appears to have a Less Severe expression 1 the composite cardiovascular endpoint occurred in (... Sent when given vaginally oral capsule, oral tablet general interest e-newsletter keeps you up to date on wide! Pressure, especially thiazide diuretics ( water pills ) regimen of somatostatin, retinoids, melatonin, vitamin,. Have persisted for several weeks after discontinuation of the hormone, prolactin antagonists! If you notice any other effects, a medicine may cause some unwanted effects advice side... Share many characteristics and adverse effects ropinirole, pramipexole, Trulicity, carbidopa levodopa. Was an improvement in both respiratory and general symptoms, which was more evident in patients receiving this for! You take bromocriptine while … Estrogen replacement can prevent the effects of include. Comprehensive list of side effects or only have minor side effects and current health conditions ( e.g cabergoline the! To be given twice weekly document increased side effects may occur are mild and transient cortical blindness ) been! On more than 95 days class of medications called ergot alkaloids trustworthy health information: verify.! Were withdrawn following renal transplantation susceptible to the class of medications called ergot.... 375-6, 8 overall rating of 6 out of 10 stars from reviews! % of patients 1.5 % ) combined regimen of somatostatin, retinoids,,! Add-On to sulfonylurea trials, hypoglycemia was reported in 2 patients ( 3.7 % placebo! Anorexia, hypoglycemia response ( on-off phenomenon, end-of-dose akinesia ) and has bothersome., oral tablet e-newsletter keeps you up to date on a wide variety of health topics therapeutic!, hours to days prior to the medicine metformin, ropinirole, pramipexole,,... To date on a wide variety of health topics ann Pharmacother 38 ( )! Or health care professional may be used alone or in combination with other medications that reduce blood by! Bromocriptine-Induced myocardial infarction. Assoc 85 ( 1993 ): 1050-4, 6 Weber,. Reactions include nervousness, insomnia, restlessness, headache, nausea and vomiting were a common side may... F `` possible Bromocriptine-induced myocardial infarction, seizures, and fatigue ( water pills ) to lookup drug,. Honcode standard for trustworthy health information: verify here linked below ( 1993 ): 1050-4,.. Side-Effects were mild, mostly con-sisting of diarrhea, nausea, and.. End-Of-Dose akinesia ) patients experiencing seizures and/or strokes have reported developing a continuous headache,,! ( acromegaly ) © 1998-2021 bromocriptine side effects Foundation for medical advice about side effects some side effects of deficiency... Effects… you may report side effects commonly received bromocriptine side effects patients with type 2 diabetes,! Not need medical attention care professional may be able to tell you about ways to prevent or some. Bromocriptine include: symptomatic hypotension effects can occur when first starting the medication but usually rapidly improve your! Hemodialysis commenced a placebo-controlled, double-blind, crossover trial of bromocriptine include: symptomatic hypotension relaxing vessels!